The bioconversion process of bioactive naringenin by whole-cells of Yarrowia lipolytica 2.2ab for the production of increased value-added compounds is successfully achieved in surface and liquid cultures. This approach is an alternative to the commercial production of these bioactive compounds from vegetable sources, which are limited due to their low concentrations and the complexity of the purification processes. The experimentation rendered seven value-added compounds in both surface and liquid bioconversion cultures. Some of the compounds produced have not been previously reported as products from the bioconversion processes, such as the case of ampelopsin. Biosynthetic pathways were suggested for the naringenin bioconversion using whole-cells of Y. lipolytica 2.2ab. Finally, the extracts obtained from the naringenin bioconversion in liquid cultures showed higher percentage of inhibition of DPPH· and ABTS· radicals up to 32.88 and 2.08 times, respectively, compared to commercial naringenin.

中文翻译：

---

使用解脂耶氏酵母2.2ab在表面和液体培养物中将柚皮素全细胞生物转化为高附加值的羟基化化合物。

在表面和液体培养中成功地完成了解脂耶氏酵母2.2ab的全细胞生物活性柚皮素的生物转化过程，以生产增加值的化合物。这种方法是从植物来源商业生产这些生物活性化合物的替代方法，由于它们的低浓度和纯化过程的复杂性而受到限制。该实验在表面和液体生物转化培养物中产生了7种增值化合物。以前尚未报道某些产生的化合物是生物转化过程的产物，例如两性霉素。建议使用解脂耶氏酵母2.2ab的全细胞进行柚皮素生物转化的生物合成途径。最后，