Purpose

To assess the current knowledge regarding medication-related osteonecrosis of the jaw (MRONJ); the adverse effects of anti-resorptive (AR) and anti-angiogenic (AA) drugs; strategies for MRONJ prevention and treatment; and perception of the dentist’s role in assisting patients who use these drugs among physicians, dentists, and nurses.

Methods

Using questionnaires, the current knowledge of MRONJ was assessed among dentists, physicians, and nurses, who were divided into group I, which included specialties that directly assist cancer patients, and group II, which included other specialties. The questionnaires assessed the characteristics of the health professionals, training time, and specialties; their knowledge of AR and AA drugs; and their knowledge of MRONJ.

Results

A total of 1370 health professionals participated in the study, including 1032 dentists, 239 physicians, and 99 nurses. Among dentists and physicians, the training time (p = 0.036 and p < 0.001, respectively) and specialization in group I domains (p < 0.001 and p < 0.001, respectively) had a significant impact on MRONJ knowledge, while nurses showed no significant impact regardless of the training time and specialty. Less than 10% of the physicians and dentists could correlate the signs and symptoms of all stages of MRONJ.

Conclusion

The findings indicated a notable lack of knowledge regarding MRONJ among dental surgeons and physicians, and especially among nurses. More experienced professionals and specialists in the areas that assist cancer patients usually have a greater understanding of the dentist’s role in MRONJ prevention, diagnosis, treatment, and patient care and will introduce or are already using AR and AA drugs.

中文翻译：

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不同卫生专业人员之间有关药物相关的颌骨坏死的最新知识。

目的

评估有关与药物有关的颌骨坏死的最新知识（MRONJ）；抗再吸收（AR）和抗血管生成（AA）药物的不良影响；MRONJ预防和治疗策略；以及对牙医在协助医师，牙医和护士中使用这些药物的患者中的作用的认识。

方法

使用调查表，在牙医，医师和护士中评估了MRONJ的当前知识，他们分为I组（包括直接帮助癌症患者的专业）和II组（包括其他专业）。问卷评估了卫生专业人员的特征，培训时间和专长；他们对AR和AA药物的了解；和他们对MRONJ的了解。

结果

共有1370名卫生专业人员参加了这项研究，其中包括1032名牙医，239名医生和99名护士。在牙医和医师中，培训时间（分别为p  = 0.036和p  <0.001）和I组领域的专业化（分别为p  <0.001和p  <0.001）对MRONJ知识有显着影响，而护士对此没有显着影响无论培训时间和专业如何。少于10％的医师和牙医可以将MRONJ各个阶段的体征和症状关联起来。

结论

调查结果表明，牙科医生和医师，尤其是护士中，对MRONJ的知识明显缺乏。在协助癌症患者方面，经验丰富的专业人士和专家通常会对牙医在MRONJ预防，诊断，治疗和患者护理中的作用有更深入的了解，并将引进或已经使用AR和AA药物。