The purpose of the EANM Dosimetry Committee Series on “Standard Operational Procedures for Dosimetry” (SOP) is to provide advice to scientists and clinicians on how to perform patient-specific absorbed dose assessments. This SOP describes image and data acquisition parameters and dosimetry calculations to determine the absorbed doses delivered to whole-body, tumour and normal organs following a therapeutic administration of 131I mIBG for the treatment of neuroblastoma or adult neuroendocrine tumours. Recommendations are based on evidence in recent literature where available and on expert opinion within the community. This SOP is intended to promote standardisation of practice within the community and as such is based on the facilities and expertise that should be available to any centre able to perform specialised treatments with radiopharmaceuticals and patient-specific dosimetry. A clinical example is given to demonstrate the application of the absorbed dose calculations.

中文翻译：

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EANM 剂量测定委员会关于神经内分泌肿瘤 131I mIBG 治疗内部剂量测定标准操作程序的系列。


EANM 剂量测定委员会“剂量测定标准操作程序”(SOP) 系列的目的是为科学家和临床医生提供如何执行患者特定吸收剂量评估的建议。该 SOP 描述了图像和数据采集参数以及剂量测定计算，以确定在 131I mIBG 治疗神经母细胞瘤或成人神经内分泌肿瘤后输送到全身、肿瘤和正常器官的吸收剂量。建议基于最新文献中的证据以及社区内的专家意见。该标准操作程序旨在促进社区内实践的标准化，因此其基础是任何能够使用放射性药物和患者特定剂量测定进行专门治疗的中心都可以使用的设施和专业知识。给出了一个临床例子来演示吸收剂量计算的应用。