A multipedal DNA walker for amplified detection of tumor exosomes.,Chemical Communications

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A multipedal DNA walker for amplified detection of tumor exosomes.
Chemical Communications ( IF 4.3 ) Pub Date : 2020-04-14 , DOI: 10.1039/d0cc01817a
Peng Miao ₁ , Yuguo Tang

Affiliation

We have fabricated an ultrasensitive exosome biosensor based on a multipedal DNA walker with a core of target exosomes. Specific recognition is achieved by introducing a CD63 aptamer and facile separation is obtained with magnetic Fe3O4@Au nanoparticles. A limit of detection down to 6/μL is obtained with excellent selectivity.

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