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Systematic review of the epidemiology of acne vulgaris.
Scientific Reports ( IF 3.8 ) Pub Date : 2020-04-01 , DOI: 10.1038/s41598-020-62715-3
Anna Hwee Sing Heng 1 , Fook Tim Chew 1
Affiliation  

A systematic review was conducted on epidemiology studies on acne obtained from a Web of Science search to study risk factors associated with acne presentation and severity. A strong association was observed between several risk factors - family history, age, BMI and skin type - and acne presentation or severity in multiple studies. The pooled odds ratio of 2.36 (95% CI 1.97-2.83) for overweight/obese BMI with reference to normal/underweight BMI and the pooled odds ratio of 2.91 (95% CI 2.58-3.28) for family history in parents with reference to no family history in parents demonstrate this strong association. In addition, a pooled odds ratio of 1.07 (95% CI 0.42-2.71) was obtained for sex (males with reference to females). However, the association between other factors, such as dietary factors and smoking, and acne presentation or severity was less clear, with inconsistent results between studies. Thus, further research is required to understand how these factors may influence the development and severity of acne. This study summarizes the potential factors that may affect the risk of acne presentation or severe acne and can help researchers and clinicians to understand the epidemiology of acne and severe acne. Furthermore, the findings can direct future acne research, with the hope of gaining insight into the pathophysiology of acne so as to develop effective acne treatments.

中文翻译:

系统评价寻常型痤疮的流行病学。

从Web of Science搜索获得的痤疮流行病学研究进行了系统的综述,以研究与痤疮表现和严重程度相关的危险因素。在多项研究中,观察到几个风险因素之间的密切相关性:家族病史,年龄,BMI和皮肤类型以及痤疮的表现或严重程度。相对于正常/体重过轻的BMI,超重/肥胖BMI的汇总比值比为2.36(95%CI 1.97-2.83),对于父母的家族史,汇总的比值比为2.91(95%CI 2.58-3.28)父母的家族史证明了这种强烈的联系。此外,性别(男性相对于女性)的合并比值比为1.07(95%CI 0.42-2.71)。但是,其他因素(例如饮食因素和吸烟)之间的关联,痤疮的表现或严重程度尚不清楚,研究之间结果不一致。因此,需要进一步的研究来了解这些因素如何影响痤疮的发生和严重程度。这项研究总结了可能影响痤疮出现或严重痤疮的风险的潜在因素,并可以帮助研究人员和临床医生了解痤疮和严重痤疮的流行病学。此外,这些发现可以指导未来的痤疮研究,希望能深入了解痤疮的病理生理学,从而开发出有效的痤疮治疗方法。这项研究总结了可能影响痤疮出现或严重痤疮的风险的潜在因素,并可以帮助研究人员和临床医生了解痤疮和严重痤疮的流行病学。此外,这些发现可以指导未来的痤疮研究,希望能深入了解痤疮的病理生理学,从而开发出有效的痤疮治疗方法。这项研究总结了可能影响痤疮出现或严重痤疮的风险的潜在因素,并可以帮助研究人员和临床医生了解痤疮和严重痤疮的流行病学。此外,这些发现可以指导未来的痤疮研究,希望能深入了解痤疮的病理生理学,从而开发出有效的痤疮治疗方法。
更新日期:2020-04-01
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