A new a bisflavan-3-ol, boerhavianane (1), was isolated from Boerhavia elegans L. The structure of the flavanol dimer was elucidated by detailed spectroscopic analysis including 1H, 13C NMR, COSY, HMQC, HMBC, and ESI-MS. Boerhavianane (1) was evaluated for its anticancer activity and demonstrated a significant reduction in the viability of breast cancer cells in a concentration-dependent manner with an IC50 value of 38.48 μg/mL. Moreover, boerhavianane (1) was also screened for DPPH antioxidant activity and acetyl cholinesterase, xanthine oxidase, urease, and α-glucosidase enzyme inhibition activities. Preliminary results showed that it exhibited significant inhibition (81.0 ± 2.0%) against urease enzyme, whereas for DPPH radical scavenging it showed moderate activity (75.0 ± 1.5%).

中文翻译：

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来自布尔哈维亚线虫的新型抗癌 Bisflavan-3-Ol

从 Boerhavia elegans L 中分离出一种新的 a bisflavan-3-ol，boerhavianane (1)。通过详细的光谱分析，包括 1H、13C NMR、COSY、HMQC、HMBC 和 ESI-MS，阐明了黄烷醇二聚体的结构。对 Boerhavianane (1) 的抗癌活性进行了评估，并证明以浓度依赖的方式显着降低乳腺癌细胞的活力，IC50 值为 38.48 μg/mL。此外，还筛选了 boerhavianane (1) 的 DPPH 抗氧化活性和乙酰胆碱酯酶、黄嘌呤氧化酶、脲酶和 α-葡萄糖苷酶抑制活性。初步结果表明，它对脲酶表现出显着的抑制作用（81.0±2.0%），而对 DPPH 自由基清除显示出中等活性（75.0±1.5%）。