Carbene intermediates have shown versatile applications in modern synthetic chemistry. Catalytic ruthenium carbene/alkyne metathesis (CAM) with readily available substrates renders an efficient procedure for the in situ generation of ruthenium vinyl carbene intermediates. Here, recent advances in synthetic applications of ruthenium-catalyzed carbene/alkyne metathesis (CAM) are highlighted. 1 Introduction 2 Ruthenium Vinyl Carbenes through Carbene/Alkyne Metathesis (CAM) 3 Nonpolar Transformations of Ruthenium Vinyl Carbenes 4 Polar Transformations of Ruthenium Vinyl Carbenes 4.1 Intramolecular Ruthenium-Catalyzed [1,5]- and [1,6]-Hydride Transfer/Cyclization 4.2 Heterocyclizations of Alkynals and Alkynones 4.3 Heterocyclizations of ortho-(Alkynyloxy)benzylamines 5 DFT Studies on the Stereoselectivity of the CAM Reaction 6 Conclusions

中文翻译：

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钌催化的卡宾/炔烃复分解 (CAM) 转化的最新进展

卡宾中间体在现代合成化学中显示出多种应用。具有容易获得的底物的催化钌卡宾/炔复分解 (CAM) 为原位生成钌乙烯基卡宾中间体提供了有效的程序。在这里，重点介绍了钌催化的卡宾/炔烃复分解 (CAM) 合成应用的最新进展。1 引言 2 钌乙烯基卡宾通过卡宾/炔烃复分解 (CAM) 3 钌乙烯基卡宾的非极性转化 4 钌乙烯基卡宾的极性转化 4.1 分子内钌催化的 [1,5]- 和 [1,6]-氢化物转移/ 4.2 炔醇和炔酮的杂环化 4.3 邻（炔氧基）苄胺的杂环化 5 CAM 反应立体选择性的 DFT 研究 6 结论