Objective

To characterize self-reported use of acute prescription medication for migraine in a sample representing the US population.

Patients and Methods

Data were obtained from the Chronic Migraine Epidemiology and Outcomes (CaMEO) Study. The CaMEO Study is an Internet-based cross-sectional longitudinal survey administered between September 17, 2012, and November 19, 2013. Demographic characteristics, migraine-related disability, symptom severity, quality of life, and psychiatric comorbidity profiles were evaluated.

Results

Data from 13,624 respondents were analyzed, including 3121 (22.9%) self-reported current users of acute prescription medication for migraine, 1719 (12.6%) previous/discontinued users, and 8784 (64.5%) who had never used acute prescription medication for migraine. Mean ± SD monthly headache frequency was 7.3±7.1 days for current users, 5.6±6.6 days for those who discontinued, and 3.9±4.9 days for respondents who never used acute prescription medication for migraine. Current users experienced the highest degree of migraine-related disability based on Migraine Disability Assessment scores and the highest levels of migraine symptom severity based on Migraine Symptom Severity Scale scores. Current users also had the highest scores on the depression and anxiety questionnaires. The most commonly reported prescription medications used or “kept on hand” by current users were triptans (47.2%; 1474 of 3121), opioids (37.3%; 1164 of 3121), nonsteroidal anti-inflammatory drugs (31.9%; 997 of 3121), and barbiturates (12.8%; 399 of 3121), with many people reporting more than 1 medication.

Conclusion

Despite reporting moderate to severe migraine-related disability and impairment, many people with migraine have never used acute prescription migraine medication. The burden related to migraine is great, especially among individuals currently using acute prescription medication for migraine.

中文翻译：

---

急性偏头痛药物使用的表征：CaMEO研究的结果。

目的

为了表征自我报告的代表美国人群的样本中偏头痛的急性处方药使用情况。

患者和方法

数据来自慢性偏头痛流行病学和结果（CaMEO）研究。CaMEO研究是一项基于互联网的横断面纵向调查，于2012年9月17日至2013年11月19日进行。评估了人口统计学特征，偏头痛相关的残疾，症状严重程度，生活质量和精神病合并症。

结果

分析了来自13,624名受访者的数据，其中包括3121（22.9％）位自报告的当前偏头痛急性处方药的当前使用者，1719位（12.6％）先前/停用的用户以及从未使用偏头痛急性处方药的8784位（64.5％） 。当前使用者的平均±SD每月头痛频率为7.3±7.1天，停用者为5.6±6.6天，从未使用偏头痛的急性处方药的受访者为3.9±4.9天。根据偏头痛残疾评估评分，当前用户经历了与偏头痛相关的残疾程度最高，而根据偏头痛症状严重程度量表评分，偏头痛症状严重程度最高。当前的用户在抑郁和焦虑问卷中得分也最高。

结论

尽管报告了中度至重度偏头痛相关的残疾和损伤，但许多偏头痛患者从未使用过急性偏头痛处方药。与偏头痛有关的负担很大，尤其是在当前使用急性处方药治疗偏头痛的个体中。