Viscous soluble dietary fibers (VSDF) have received much attention for their potential role in energy regulation through the reduction of energy intake due to increased satiety. The aim of our study was to investigate the effects of low and high viscosities of xanthan and guar gum solutions on postprandial nutrient intake and plasma biomarkers of nutrient metabolism by an in vivo animal experiment. This study examined the effects of short-term and long-term intake of different VSDF on metabolism and physical condition in rats. On the third day the 4 h food intake (FI) after gavage of the high viscosity xanthan gum (HX) group was decreased from 13.07 g to 6.79 g and the blood glucose (BG) 30 min postprandial was lowered from 14.1 mmol/L to 7.9 mmol/L compared to Control. The amount of gastrointestinal chyme in the HX group was significantly higher than the other groups after 2 h of gavage. The long-term (3 weeks) consumption of VSDF reduced the rats' FI, body weight, fasting blood glucose, apparent protein digestibility, insulin and leptin concentrations, indicating that VSDF may reduce weight gain by inhibiting nutrient digestion. The long-term intake of VSDF increased the length of the small intestine. HX group had the lowest weight gain and nutrient digestion than the other groups.

粘性可溶性膳食纤维（VSDF）由于其通过增加饱腹感而减少能量摄入而在能量调节中的潜在作用而备受关注。我们研究的目的是通过体内研究低粘度和高粘度的黄原胶和瓜尔胶溶液对餐后营养摄入和营养代谢血浆生物标志物的影响动物实验。这项研究检查了短期和长期摄入不同VSDF对大鼠新陈代谢和身体状况的影响。第三天，高粘度黄原胶（HX）组灌胃后的4小时食物摄入量（FI）从13.07 g降低至6.79 g，餐后30分钟的血糖（BG）从14.1 mmol / L降低至与对照组相比为7.9 mmol / L。灌胃2 h后HX组的胃肠食糜含量明显高于其他组。长期（3周）食用VSDF会降低大鼠的FI，体重，空腹血糖，表观蛋白质消化率，胰岛素和瘦素浓度，这表明VSDF可能通过抑制营养物质消化来减轻体重增加。长期摄入VSDF会增加小肠的长度。