An efficient fluorescent probe, 3, 3-bis(4-hydroxyphenyl)-2-benzofuran-1-one-isoquinoline-1-carbohydrazide hydrazine (L), has been prepared for the selective sensing of Al³⁺ in DMSO-H₂O (90:10, v/v) solution. The 1:2 stoichiometry of L and Al³⁺ was determined from Job's plot experiments and ESI-MS. The binding constants was observed as 7.106 × 10¹⁰ M⁻², and the detection limit is 9.79 × 10⁻⁹ M. Moreover, the as-prepared probe shows high sensitivity to Al³⁺ both in acidic and neutral conditions. In addition, the as-prepared probe with good biological compatibility shows effective imaging of Al³⁺ in living cells.

制备了一种高效的荧光探针3，3-双（4-羟苯基）-2-苯并呋喃-1-酮-异喹啉-1-甲酰肼（L），用于选择性检测DMSO-H _2中的Al ³⁺。O（90:10，v / v）解决方案。L和Al ^3+的化学计量比为1：2，由Job的绘图实验和ESI-MS确定。观察到结合常数为7.106×10 ¹⁰ M ^-2，检测极限为9.79×10 ^-9M。此外，所制备的探针在酸性和中性条件下均显示出对Al ^3+的高灵敏度。另外，所制备的具有良好生物相容性的探针显示出对Al ^3+的有效成像 在活细胞中。