当前位置: X-MOL 学术Org. Lett. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Sulfoxonium-Ylide-Directed C-H Activation and Tandem (4 + 1) Annulation.
Organic Letters ( IF 4.9 ) Pub Date : 2020-03-31 , DOI: 10.1021/acs.orglett.0c00451
Vinayak Hanchate 1 , Ravi Devarajappa 1 , Kandikere Ramaiah Prabhu 1
Affiliation  

Rh(III)-catalyzed C–H activation and cyclization of sulfoxonium ylide with acrylates leads to an efficient synthesis of indanone derivatives. The reaction proceeds under mild and external metal-oxidant-free conditions. The sulfoxonium ylide acts as a traceless directing group as well as an internal oxidant. (4 + 1) Annulation after C–H activation leads to the formation of a carbocyclic ring, and the byproduct obtained is DMSO, which can be easily separated.

中文翻译:

ulf氧鎓盐控制的CH活化和串联(4 +1)环空。

Rh(III)催化的C–H活化和亚硫酸亚砜与丙烯酸酯的环化作用导致茚满酮衍生物的有效合成。反应在温和且无外部金属氧化剂的条件下进行。磺酸亚砜鎓盐充当无痕的导向基团以及内部氧化剂。(4 +1)C–H活化后的环状结构导致形成碳环,而获得的副产物为DMSO,可轻松分离。
更新日期:2020-04-24
down
wechat
bug