We thank the authors for their interest in our study and for their comments. Wiesweg and colleagues correctly reported that the minor allele frequency of both p.T1010I and p.R988C MET variants is close to 1% in the European population, but these mutations were described also as somatic (T1010I:

中文翻译：

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克唑替尼在ROS1和MET失控的NSCLC中的反应

我们感谢作者对我们的研究感兴趣以及他们的评论。Wiesweg及其同事正确地报告了p.T1010I和p.R988C MET变体的次要等位基因频率在欧洲人群中接近1％，但是这些突变也被描述为体细胞性（T1010I：