Proteomic and genomic biomarkers for Non-Small Cell Lung Cancer: Peroxiredoxin, Haptoglobin, and Alpha-1 antitrypsin.,Cancer Medicine

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Proteomic and genomic biomarkers for Non-Small Cell Lung Cancer: Peroxiredoxin, Haptoglobin, and Alpha-1 antitrypsin.
Cancer Medicine ( IF 2.9 ) Pub Date : 2020-03-30 , DOI: 10.1002/cam4.3019
Zahra Najafi ₁ , Abdolreza Mohamadnia _{2,

3} , Rahim Ahmadi ₁ , Minoo Mahmoudi ₁ , Naghmeh Bahrami _{4,

5} , Adnan Khosravi ₆ , Hamidreza Jamaati ₂ , Payam Tabarsi ₇ , Mehdi Kazem Pour Dizaji ₈ , Sadegh Shirian _{9,

10,

11}

Affiliation

Department of Biology, Faculty of Basic Sciences, Hamedan Branch, Islamic Azad University, Hamedan, Iran.
Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Craniomaxillofacial Research Center, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Tobacco Prevention and Control Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Biostatistics Department, Mycobacteriology Research Center, National Research Institute of Tuberculosis and Lung Diseases, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Pathology, School of Veterinary Medicine, Shahrekord University, Shahrekord, Iran.
Shiraz Molecular Pathology Research Center, Dr Daneshbod Lab, Shiraz, Iran.
Shefa Neuroscience Research Center, Tehran, Iran.

The development of lung cancer is a multifactorial process that involves the environmental and genetic factors. The mortality rate of this cancer is higher than breast, colorectal, and prostate cancers. In this study, we try to analyze the proteome of patients with Non‐Small Cell Lung Cancer (NSCLC) and compare it with the healthy samples.

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