Background

Physical activity (PA) is important to maintaining functional independence. It is not clear how patterns of change in late-life PA are associated with contemporaneous changes in physical performance measures.

Methods

Self-reported PA, gait speed, grip strength, timed chair stand, and leg power were assessed in 3,865 men aged ≥ 65 years at baseline (2000-02) and Year 7 (2007-09). Group-based trajectory modeling, using up to four PA measures over this period, identified PA trajectories. Multivariate linear regression models (adjusted least square mean [95% CI]) described associations between PA trajectories and concurrent changes in performance.

Results

Three discrete PA patterns were identified, all with declining PA. Linear declines in each performance measure (baseline to Year 7) were observed across all three PA groups, but there was some variability in the rate of decline. Multivariate models assessing the graded response by PA trajectory showed a trend where the high-activity group had the smallest declines in performance while the low-activity group had the largest (p-for trend<.03). Changes in the high-activity group were: gait speed (-0.10 m/s [-0.12, -0.08]), grip strength (-3.79kg [-4.35, -3.23]), and chair stands (-0.38 [-0.50, -0.25]); while changes in the low-activity group were: gait speed (-0.16 [-0.17, -0.14]), grip strength (-4.83kg [-5.10, -4.55]), and chair stands (-0.53 [ -0.59, -0.46]). Between-group differences in leg power trajectories across PA patterns were not significant.

Conclusions

Declines in functional performance were higher among those with lower PA trajectories, providing further evidence for the interrelationship between changes in PA and performance during old age.

中文翻译：

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老年人的体育锻炼轨迹和体育锻炼的相关变化：MrOS研究

背景

身体活动（PA）对于维持功能独立性很重要。尚不清楚晚期PA的变化模式与物理性能指标的同期变化如何相关。

方法

在基线（2000-02）和7年级（2007-09）对3865名年龄≥65岁的男性进行了自我报告的PA，步态速度，握力，定时椅站立和腿部力量的评估。基于组的轨迹建模，在此期间最多使用四个PA量度，以识别PA轨迹。多元线性回归模型（调整后的最小二乘均方[95％CI]）描述了PA轨迹与性能同时变化之间的关联。

结果

确定了三个离散的PA模式，所有PA模式均下降。在所有三个PA组中，每个绩效指标（基线到7年级）均呈线性下降，但下降率存在一定差异。通过PA轨迹评估分级反应的多变量模型显示出一种趋势，其中高活动组的表现下降最小，而低活动组的表现下降最大（p-趋势<.03）。高强度活动组的变化是：步态速度（-0.10 m / s [-0.12，-0.08]），握力（-3.79kg [-4.35，-3.23]）和椅子站立（-0.38 [-0.50] ，-0.25]）；低强度运动组的变化包括：步态速度（-0.16 [-0.17，-0.14]），握力（-4.83kg [-5.10，-4.55]）和椅子站立（-0.53 [-0.59，- 0.46]）。

结论

具有较低PA轨迹的患者的功能性能下降较高，这为PA的变化与老年性能之间的相互关系提供了进一步的证据。