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Trained immunity by HSCs.
Nature Reviews Immunology ( IF 67.7 ) Pub Date : 2020-05-01 , DOI: 10.1038/s41577-020-0299-0 Lucy Bird 1
Nature Reviews Immunology ( IF 67.7 ) Pub Date : 2020-05-01 , DOI: 10.1038/s41577-020-0299-0 Lucy Bird 1
Affiliation
New research suggests that haematopoietic stem cells (HSCs) can contribute to trained immunity. Stimulation with lipopolysaccharide establishes long-lasting epigenetic changes in HSCs that confer improved responsiveness to secondary stimulation.
中文翻译:
HSC训练有素的免疫力。
新的研究表明,造血干细胞(HSC)可以有助于训练有素的免疫力。用脂多糖刺激可在HSC中建立持久的表观遗传学变化,从而改善对次级刺激的反应性。
更新日期:2020-03-31
中文翻译:
HSC训练有素的免疫力。
新的研究表明,造血干细胞(HSC)可以有助于训练有素的免疫力。用脂多糖刺激可在HSC中建立持久的表观遗传学变化,从而改善对次级刺激的反应性。