G protein-coupled receptors (GPCRs) are integral membrane proteins that mediate many responses of cells to external stimuli (1). The fundamental role of GPCRs in regulating human cellular processes makes them high-value targets for drugs (2). GPCRs are highly dynamic entities, and thus, determination of high-resolution structures of GPCRs in complex...

中文翻译：

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寻求高分辨率的G蛋白偶联受体G蛋白结构[生物物理学和计算生物学]

G蛋白偶联受体（GPCR）是整合性膜蛋白，可介导细胞对外部刺激的许多反应（1）。GPCR在调节人类细胞过程中的基本作用使其成为药物的高价值靶标（2）。GPCR是高度动态的实体，因此，可以确定复杂环境中GPCR的高分辨率结构。