Owing to frequent contact with blood, the external working medium easily adheres to medical devices such as scalpels and stents, which possibly reduces their performance. To solve this problem and with inspiration from the superhydrophobic and self-cleaning properties of natural lotus leaves, a novel surface composed of laser-patterned (LP) microstructures, with chromium nitride (CrN) films deposited on top, was fabricated on 316 L stainless steel by combining laser patterning and magnetron sputtering. A self-designed circular pattern array was used to generate the LP microstructures. Then, the effects of five key processing parameters, such as the diameter of the circular pattern, spacing of the circular pattern, laser fluence, laser scanning velocity and number of scans, on the wettability of the LP/CrN surface were evaluated using an L₁₆ (4⁵) orthogonal experiment, after which the surface was optimized to further enhance hydrophobicity and serum repellence. The optimized surface strongly corresponded with the Cassie-Baxter model and demonstrated a water (serum) contact angle of 147.7 ± 1.1° (144.2 ± 0.8°) and roll-off angle of 10.8 ± 1.7° (17.1 ± 3.1°), thus showing strongly hydrophobic and serum-repelling characteristics. Moreover, the optimized surface had a weak coffee-stain effect after 60 min of evaporation and exhibited remarkable corrosion resistance in a 3.5 wt% NaCl solution via a potentiodynamic polarization method. This study provides useful insight into the fabrication of a hydrophobic and serum-repelling surface, which can be used to address the problem of blood-adhesion on medical devices.

由于经常与血液接触，外部工作介质容易粘附到手术刀和支架等医疗设备上，这可能会降低其性能。为了解决这个问题，并从天然荷叶的超疏水性和自清洁特性中获得启发，在316 L不锈钢上制作了一种由激光图案（LP）微结构组成且顶部沉积有氮化铬（CrN）膜的新型表面。结合了激光图案化和磁控溅射技术。自行设计的圆形图案阵列用于生成LP微结构。然后，使用圆弧形图案评估了五个关键加工参数（如圆形图案的直径，圆形图案的间距，激光通量，激光扫描速度和扫描次数）对LP / CrN表面的润湿性的影响。L ₁₆（4 ⁵）正交实验，然后对其表面进行优化，以进一步增强疏水性和抗血清性。优化后的表面与Cassie-Baxter模型非常吻合，并显示出147.7±1.1°（144.2±0.8°）的水（血清）接触角和10.8±1.7°（17.1±3.1°）的滑落角。具有强疏水性和抗血清性。此外，优化的表面在蒸发60分钟后的咖啡污渍效果较弱，并且通过电位极化方法在3.5 wt％的NaCl溶液中表现出显着的耐腐蚀性。这项研究为疏水和抗血清表面的制造提供了有用的见识，可用于解决医疗器械上的血液粘附问题。