Associations between serum phosphorus level and the incidence of ischemic stroke are not clear. This study aimed to measure serum phosphorus, vitamin D3, and uric acid levels in ischemic stroke patients compared to a population without ischemic stroke. In this cross-sectional study, 133 patients admitted to a neurology ward with the diagnosis of ischemic stroke were compared with a control group comprising 133 age- and gender-matching individuals. The presence of ischemic stroke was confirmed by a neurologist based on clinical signs, symptoms, brain CT scan, and MRI. Blood samples were taken from all patients in the first 24 h of admission to measure serum phosphorus, vitamin D3, calcium, and uric acid levels. According to the results of this study, uric acid medians in patients with stroke and controls were 4.9 [3.8–6.4] and 3.9 [3.5–4.9] mg/dL, respectively (p < 0.001). Median phosphorus and vitamin D levels were significantly lower in stroke patients than the controls (3.6 [3.02–4.21] vs. 4.2 [3.8–4.6]) and (15.1 [8.2–27.9] vs. 22.7 [10.4–39.2]), respectively. Multiple logistic regression analysis showed that the ischemic stroke was positively associated with the vitamin D level and negatively correlated with the uric acid level. The phosphorus level was not significantly predictive of ischemic stroke. Lower serum levels of vitamin D3 and higher levels of uric acid were associated with ischemic stroke. There are still unknowns about the role of these indicators on ischemic stroke and it requires further studies.

中文翻译：

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脑血管疾病：血清磷，维生素D和尿酸水平如何导致缺血性中风。

血清磷水平与缺血性中风发生率之间的关联尚不清楚。这项研究旨在测量缺血性中风患者与没有缺血性中风的人群相比的血清磷，维生素D3和尿酸水平。在这项横断面研究中，将133例诊断为缺血性中风的神经科病房患者与133个年龄和性别相匹配的个体进行了比较。神经科医生根据临床体征，症状，脑部CT扫描和MRI证实了缺血性中风的存在。在入院的最初24小时内从所有患者中采集血样，以测量血清磷，维生素D3，钙和尿酸水平。根据这项研究的结果，中风和中风患者的尿酸中位数分别为4.9 [3.8-6.4]和3.9 [3.5-4.9] mg / dL，分别为（p <0.001）。脑卒中患者的中值磷和维生素D水平分别显着低于对照组（3.6 [3.02-4.21] vs. 4.2 [3.8-4.6]）和（15.1 [8.2-27.9] vs. 22.7 [10.4-39.2]）。 。多元logistic回归分析表明，缺血性中风与维生素D水平呈正相关，与尿酸水平呈负相关。磷水平不能显着预测缺血性中风。血清维生素D3降低和尿酸升高与缺血性中风有关。这些指标在缺血性卒中中的作用仍然未知，需要进一步研究。1 [8.2-27.9]与22.7 [10.4-39.2]）。多元logistic回归分析表明，缺血性中风与维生素D水平呈正相关，与尿酸水平呈负相关。磷水平不能显着预测缺血性中风。血清维生素D3降低和尿酸升高与缺血性中风有关。这些指标在缺血性卒中中的作用仍然未知，需要进一步研究。1 [8.2-27.9]与22.7 [10.4-39.2]）。多元logistic回归分析表明，缺血性中风与维生素D水平呈正相关，与尿酸水平呈负相关。磷水平不能显着预测缺血性中风。血清维生素D3降低和尿酸升高与缺血性中风有关。这些指标在缺血性卒中中的作用仍然未知，需要进一步研究。血清维生素D3降低和尿酸升高与缺血性中风有关。这些指标在缺血性卒中中的作用仍然未知，需要进一步研究。血清维生素D3降低和尿酸升高与缺血性中风有关。这些指标在缺血性卒中中的作用仍然未知，需要进一步研究。