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Rhodium(III)‐Catalyzed Oxidative C(sp3)−H Alkenylation of 8‐Methylquinolines with Maleimides Under Aerobic Conditions
Advanced Synthesis & Catalysis ( IF 5.4 ) Pub Date : 2020-03-29 , DOI: 10.1002/adsc.202000283
Baode Shan 1 , Baotao Kang 1 , Mingyue Song 1 , Rui Wang 1 , Guozhu Chen 1 , Cuncheng Li 1 , Huaiqing Zhao 1, 2
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A rhodium(III)‐catalyzed C(sp3)−H alkenylation of 8‐methylquinolines with electron‐deficient maleimides has been accomplished with the combination of copper acetate, 2,2,6,6‐tetramethylpiperidine‐1‐oxyl and oxygen as the oxidant. A variety of maleimides react with various 8‐methylquinolines to furnish the corresponding alkenylated products in moderate to good yields.

中文翻译:

铑(III)在好氧条件下用马来酰亚胺催化8-甲基喹啉的氧化C(sp3-)-H烯基化反应

铑(III)催化的8-甲基喹啉的C(sp 3)-H烯基与缺电子的马来酰亚胺的结合是由乙酸铜,2,2,6,6-四甲基哌啶-1-氧和氧氧化剂。各种马来酰亚胺与各种8-甲基喹啉反应,以中等至良好的产率提供相应的烯基化产物。
更新日期:2020-03-29
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