The synthesis and properties of β-amino acids have drawn considerable attention owing to their ubiquitous presence in naturally occurring products of biological importance. While β3-amino acids can be readily prepared from α-amino acids via one-carbon homologation, the synthesis of β2-amino acids generally requires multistep efforts. This review focuses on the recent advances in the synthesis of β2-amino acids and their derivatives from substituted β-nitropropionate analogues obtained from the stereoselective transformation of β-nitroacrylates.

中文翻译：

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从β-硝基丙烯酸酯衍生物立体选择性合成β2-氨基酸衍生物的最新进展。

由于β-氨基酸普遍存在于具有生物学重要性的天然产物中，因此其合成和性质引起了相当大的关注。尽管可以通过一碳同系物很容易地从α-氨基酸制备β3-氨基酸，但是β2-氨基酸的合成通常需要多步努力。这篇综述着重于由β-硝基丙烯酸酯的立体选择性转化获得的取代的β-硝基丙酸酯类似物合成β2-氨基酸及其衍生物的最新进展。