To the Editor We read with great interest the article by Paulin et al,¹ who examined the association between long-term ozone exposure and the respiratory health of smokers, finding that higher ozone exposure was significantly associated with lower lung function and more emphysema and air trapping. The findings of this article¹ underscore the need for enhanced meteorological monitoring on ground ozone concentrations as well as the need for early detection and targeted intervention of respiratory diseases in vulnerable members of society to reduce the escalating burden of respiratory diseases worldwide. However, from the viewpoint of data interpretation and extrapolation, we have 2 concerns.

致编辑我们非常感兴趣地阅读了Paulin等人的文章[ ^1]，该文章研究了长期臭氧暴露与吸烟者呼吸健康之间的关系，发现更高的臭氧暴露与较低的肺功能以及更多的肺气肿和空气有关诱捕。该文章¹的调查结果强调，需要加强对地面臭氧浓度的气象监测，并需要对社会弱势群体的呼吸道疾病进行早期发现和有针对性的干预，以减轻全球范围内不断升级的呼吸道疾病负担。但是，从数据解释和外推的角度来看，我们有两个问题。