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Clinical aspects, diagnosis and management of Loxosceles spider envenomation: literature and case review.
Archives of Toxicology ( IF 4.8 ) Pub Date : 2020-03-30 , DOI: 10.1007/s00204-020-02719-0
Priscila Hess Lopes 1 , Carla Cristina Squaiella-Baptistão 1 , Mário Octávio Thá Marques 2 , Denise V Tambourgi 1
Affiliation  

Abstract

The genus Loxosceles comprises 140 species widely distributed around the world. These spiders are nocturnal, sedentary and remarkably nonaggressive, although they cause accidents in humans with wide degrees of severity, generating signs and symptoms that define the clinical condition known as loxoscelism. Its local signs and symptoms were first reported in 1872, and over the years, a large medical literature has been accumulated; unfortunately, it is not always trustworthy. Assessing the reliability of such information, we reviewed 120 case reports of loxoscelism published in 84 articles over the past 20 years. This search allowed us to gather information on the clinical aspects, diagnosis and treatment of loxoscelism, showing that the severity of these accidents has multiple degrees and that it is influenced by many factors. Thus, coupled with epidemiological and species occurrence information, this study can be a useful tool for the clinical practice of loxoscelism. It may support and provide a multidisciplinary view that should be taken into consideration when establishing the therapeutic approach in cases of Loxosceles envenomation.



中文翻译:

临床研究,蛇蝎蜘蛛毒液的诊断和处理:文献和病例回顾。

摘要

狐尾藻属包含140种,广泛分布于世界各地。这些蜘蛛是夜行性的,久坐的并且非常不进取,尽管它们在严重程度严重的人类中引起事故,并产生定义了临床症状的迹象和症状,称为“骨质疏松症”。其局部症状和体征于1872年首次报道,多年来,已积累了大量医学文献。不幸的是,它并不总是值得信赖的。评估此类信息的可靠性,我们回顾了过去20年中发表在84篇文章中的120例低氧血症病例报告。这项搜索使我们能够收集有关骨质疏松症的临床方面,诊断和治疗的信息,表明这些事故的严重程度具有多个程度,并且受许多因素影响。从而,结合流行病学和物种发生信息,该研究可以作为低氧血症临床实践的有用工具。它可能支持并提供多学科的观点,在以下情况下建立治疗方法时应予以考虑凤尾虫的毒液。

更新日期:2020-03-31
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