Abstract In the present study, a novel hexagonal mesoporous silica (HMS), functionalized by nitrilotriacetic acid anhydride (NTAA) and 3-aminopropyltrimethoxysilane (APTES), was synthesized (NH2/HMS/NTAA) and applied for the adsorption of bovine serum albumin (BSA). XRD, BET, SEM, TEM and FTIR analysis were applied to identify the structure and morphology of the synthesized nano-adsorbent. The effect of some basic parameters, such as pH of the BSA solution, adsorbent dosage, contact time and temperature on the adsorption of BSA were investigated. After modification, the BET surface area of the HMS was reduced from 885 m2/g to 51 m2/g which can be attributed to the existence of NTTA and amine groups that limited the adsorption of nitrogen molecules. The results of the equilibrium study proved that the adsorption of BSA on NH2/HMS/NTAA followed a Langmuir isotherm with a high maximum adsorption capacity of 1000 mg/g, which proves mono-layer adsorption. Kinetic and thermodynamic studies also demonstrated that a pseudo-second order kinetic model was the predominant model and the adsorption process was exothermic, physical and spontaneous.

中文翻译：

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双功能化HMS、次氮基三乙酸-胺改性六方介孔硅酸盐吸附牛血清白蛋白

摘要 在本研究中，合成了一种由次氮基三乙酸酐 (NTAA) 和 3-氨基丙基三甲氧基硅烷 (APTES) 功能化的新型六方介孔二氧化硅 (HMS)（NH2/HMS/NTAA），并将其应用于牛血清白蛋白的吸附。 BSA）。应用XRD、BET、SEM、TEM和FTIR分析来鉴定合成的纳米吸附剂的结构和形貌。研究了BSA溶液的pH值、吸附剂用量、接触时间和温度等基本参数对BSA吸附的影响。改性后，HMS 的 BET 表面积从 885 m2/g 减少到 51 m2/g，这可归因于 NTTA 和胺基团的存在，限制了氮分子的吸附。平衡研究结果证明BSA在NH2/HMS/NTAA上的吸附遵循Langmuir等温线，最大吸附容量高达1000 mg/g，证明是单层吸附。动力学和热力学研究还表明，伪二级动力学模型是主要模型，吸附过程是放热、物理和自发的。