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Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfunction and bacterial translocation [Applied Biological Sciences]
Proceedings of the National Academy of Sciences of the United States of America ( IF 11.1 ) Pub Date : 2020-03-27
Yuxin Wang, Jun Yang, Weicang Wang, Katherine Z. Sanidad, Maris A. Cinelli, Debin Wan, Sung Hee Hwang, Daeyoung Kim, Kin Sing Stephen Lee, Hang Xiao, Bruce D. Hammock, Guodong Zhang

Intestinal barrier dysfunction, which leads to translocation of bacteria or toxic bacterial products from the gut into bloodstream and results in systemic inflammation, is a key pathogenic factor in many human diseases. However, the molecular mechanisms leading to intestinal barrier defects are not well understood, and there are currently no...

中文翻译:

可溶性环氧化物水解酶是肥胖引起的肠屏障功能障碍和细菌易位的内源性调节剂[应用生物学]

肠屏障功能障碍是导致许多人类疾病的关键致病因素,导致肠道细菌或有毒细菌产物从肠道转移到血液中并导致全身性炎症。但是,导致肠屏障缺陷的分子机制尚不十分清楚,目前尚无...
更新日期:2020-03-28
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