The frequent occurrence of pharmaceuticals and personal care products (PPCPs) in domestic wastewater has caused great concern. In this study, the removal of two typical pharmaceuticals (Roxithromycin, ROX; Sulfamethoxazole, SMZ) in aerobic granular sludge (AGS) reactors was investigated under condition of different C/N (carbon to nitrogen) ratios. Results showed that higher removal efficiencies of ROX and SMZ (95.2 % and 92.9 %) were achieved in the AGS reactor fed with low C/N influent. Batch experiments further revealed that the removal of ROX was influenced by the adsorption ability of the AGS while SMZ removal was mainly enhanced by biodegradation process. Analysis of extracellular polymeric substances (EPS) showed that the humic acid-like substances were enriched under low C/N condition, which was in accordance with dynamic change of microbial community. The microbes, like Thauera spp. and Xanthomonadaceae, were highly enriched in the reactor with high nitrogen loading rate and functioned as refractory organics degrader. Overall, the AGS process could achieve enhanced pharmaceuticals removal performance by the regulation of microbial community under low C/N influent, which provides insights into a feasible solution for simultaneous removal of nitrogen and trace organic pollutants in AGS reactor.

中文翻译：

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在低C / N比进水条件下，通过好氧颗粒污泥的成形微生物群落增强PPCPs的去除。

生活污水中频繁出现的药品和个人护理产品（PPCP）引起了人们的极大关注。在这项研究中，研究了在C / N（碳氮比）不同的条件下，好氧颗粒污泥（AGS）反应器中两种典型药物（罗红霉素，ROX，磺胺甲恶唑，SMZ）的去除方法。结果表明，在低C / N进料的AGS反应器中，ROX和SMZ的去除效率更高（分别为95.2％和92.9％）。批处理实验进一步表明，ROX的去除受AGS吸附能力的影响，而SMZ的去除主要受生物降解过程的影响。对细胞外聚合物质（EPS）的分析表明，在低C / N条件下，类腐殖酸类物质富集，这与微生物群落的动态变化是一致的。微生物，如Thauera spp。Xanthomonadaceae，和Xanthomonadaceae，在氮含量高的反应器中高度富集，并用作难降解的有机物降解剂。总体而言，AGS工艺可以通过在低C / N进水量下调节微生物群落来提高药物去除性能，这为在AGS反应器中同时去除氮和微量有机污染物的可行解决方案提供了见识。