INTRODUCTION Too frequent HbA1c measurements may lead to unnecessary treatment modifications of diabetic patients. The aim of this study was to estimate the percentage of falsely elevated HbA1c results in two hospitals, Landeskrankenhaus/Uniklinikum Salzburg (LKH) and Landesklinik St. Veit (STV), as well as to retrospectively investigate the effect of an automated and an educative 60-day re-testing interval (RTI). METHODS The amount of estimated falsely elevated results (eFER), based on odds calculated using the baseline and the follow-up values and the time between these measurements, the number of HbA1c re-testings within 60 days as well as the overall number of ordered and performed HbA1c analyses were calculated. In LKH, an automated algorithm cancelling inappropriate HbA1c testing was applied, and in STV, educational actions were taken. RESULTS Before RTI-implementation, eFER were 0.9% and 2.1% and within-60-days-re-testing were 15.0% and 7.4% of cases in LKH and STV, respectively. After RTI-implementation, these numbers decreased to 0.2% (p < .001) and 1.8% (p = .869) and within-60-days-re-testing decreased to 1.1% (p < .001) and 3.6% (p = .003) in LKH and STV, respectively. Median monthly HbA1c measurements decreased by 15.8% (p < .001) and 21.1% (p = .002) in LKH and STV, respectively. CONCLUSION Both the educational and the automated 60-day-RTI were proven to be efficient in reducing overall HbA1c measurements, re-testing within 60 days and eFER.

中文翻译：

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通过应用自动化且具教育意义的HbA1c重新测试间隔，降低糖尿病患者中HbA1c错误升高的可能性。

简介太频繁的HbA1c测量可能会导致糖尿病患者不必要的治疗修改。这项研究的目的是评估Landeskrankenhaus / Uniklinikum Salzburg（LKH）和Landesklinik St. Veit（STV）这两家医院的HbA1c结果虚假升高的百分比，并回顾性研究自动化和教育性60的效果。天重新测试间隔（RTI）。方法根据使用基线和随访值计算的几率和两次测量之间的时间，60天之内HbA1c复检次数以及订购的总数，估计的假升高结果（eFER）的数量并进行了HbA1c分析。在LKH中，应用了取消不适当的HbA1c测试的自动算法，在STV中，采取了教育措施。结果在LKH和STV中，在实施RTI前，eFER分别为0.9％和2.1％，在60天之内重新测试分别为15.0％和7.4％。实施RTI后，这些数字分别下降到0.2％（p <.001）和1.8％（p = .869），并且在60天之内的重新测试下降到1.1％（p <.001）和3.6％（p p = 0.003）分别在LKH和STV中显示。LKH和STV的每月HbA1c中位数测量值分别降低了15.8％（p <.001）和21.1％（p = .002）。结论事实证明，教育和自动60天RTI均可有效降低HbA1c的总体测量值，在60天内重新测试和进行eFER。LKH和STV的8％（p = .869）和60天之内的重新测试分别降至1.1％（p <.001）和3.6％（p = .003）。LKH和STV的每月HbA1c中位数测量值分别降低了15.8％（p <.001）和21.1％（p = .002）。结论事实证明，教育和自动进行60天RTI均可有效减少HbA1c的总体测量，在60天内重新测试和进行eFER。LKH和STV的8％（p = .869）和60天之内的重新测试分别降至1.1％（p <.001）和3.6％（p = .003）。LKH和STV的每月HbA1c中位数测量值分别降低了15.8％（p <.001）和21.1％（p = .002）。结论事实证明，教育和自动60天RTI均可有效降低HbA1c的总体测量值，在60天内重新测试和进行eFER。