We study sharp-edge structures that are used in microfluidic systems for particle and cell manipulation. Experiments show that oscillating sharp-edges can attract or repel particles suspended in a microfluidic channel. This effect is assumed to be caused by acoustic radiation forces produced by sharp-edges. We propose a theory that allows the evaluation of acoustic radiation forces produced by sharp-edge structures on elastic particles at different methods of acoustic actuation. We show that the effect of attraction or repulsion is determined by the method of actuation and the material properties of particles. The proposed theory provides a general understanding on how to efficiently use this effect for various microfluidic applications. We also provide experimental data to validate the theory.

中文翻译：

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微流体系统中尖锐边缘结构产生的声辐射力

我们研究了微流控系统中用于颗粒和细胞处理的尖端结构。实验表明，振荡的锋利边缘可以吸引或排斥悬浮在微流体通道中的颗粒。假定此效果是由锐边产生的声辐射力引起的。我们提出了一种理论，该理论允许以不同的声激励方法评估弹性颗粒上的尖锐边缘结构产生的声辐射力。我们表明吸引或排斥的影响是由驱动方法和颗粒的材料特性决定的。提出的理论提供了有关如何有效地将这种效应用于各种微流体应用的一般理解。我们还提供实验数据以验证该理论。