The photoredox chloroacylation of alkenes has been developed as a substitute for the Friedel–Crafts acylation of alkenes to β-chloroketones. The direct generation of acyl radical species from acid chlorides under the photoredox conditions allows the formation of β-chloroketones without dehydrochlorination with the help of KHCO₃. The synthetic utility of the current method is demonstrated in the one-pot synthesis of dihydroisoxazole, dihydropyrazole, and dihydropyrimidine-2-thione in 1 mmol scale.

中文翻译：

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可见光促进烯烃的Friedel-Crafts型氯酰化为β-氯酮

烯烃的光氧化还原氯酰化已被开发出来，可以替代烯烃的Friedel-Crafts酰化为β-氯酮。在光氧化还原条件下，由酰氯直接生成酰基自由基种类，无需借助KHCO ₃进行脱氯化氢即可形成β-氯酮。当前方法的合成效用已在1毫摩尔规模的一锅合成二氢异恶唑，二氢吡唑和二氢嘧啶-2-硫酮中得到了证明。