Cancer has been one of the leading causes of death globally, with metastases and recurrences contributing to this result. The detection of circulating tumor cells (CTCs), which have been implicated as a major population of cells that is responsible for seeding and migration of tumor sites, could contribute to early detection of metastasis and recurrences, consequently increasing the chances of cure. This review article focuses on the current progress in microfluidics technology in CTCs diagnostics, extending to the use of nanomaterials and surface modification techniques for diagnostic applications, with an emphasis on the importance of integrating microchannels, nanomaterials, and surface modification techniques in the isolating and detecting of CTCs.

中文翻译：

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用于循环肿瘤细胞分离和检测的微流体和纳米材料技术。


癌症一直是全球死亡的主要原因之一，转移和复发导致了这一结果。循环肿瘤细胞（CTC）被认为是负责肿瘤部位播种和迁移的主要细胞群，其检测可能有助于早期发现转移和复发，从而增加治愈的机会。本文重点介绍了微流控技术在 CTC 诊断中的最新进展，扩展到纳米材料和表面修饰技术在诊断应用中的使用，重点介绍了集成微通道、纳米材料和表面修饰技术在分离和检测中的重要性。 CTC 的数量。