Dynamic covalent polymer networks exhibit unusual adaptability while maintaining the robustness of conventional covalent networks. Typically, their network topology is statistically nonchangeable, and their material properties are therefore nonprogrammable. By introducing topological heterogeneity, we demonstrate a concept of topology isomerizable network (TIN) that can be programmed into many topological states. Using a photo-latent catalyst that controls the isomerization reaction, spatiotemporal manipulation of the topology is realized. The overall result is that the network polymer can be programmed into numerous polymers with distinctive and spatially definable (thermo-) mechanical properties. Among many opportunities for practical applications, the unique attributes of TIN can be explored for use as shape-shifting structures, adaptive robotic arms, and fracture-resistant stretchable devices, showing a high degree of design versatility. The TIN concept enriches the design of polymers, with potential expansion into other materials with variations in dynamic covalent chemistries, isomerizable topologies, and programmable macroscopic properties.

动态共价聚合物网络表现出不同寻常的适应性，同时保持了传统共价网络的稳健性。通常，它们的网络拓扑在统计上是不可改变的，因此它们的材料属性是不可编程的。通过引入拓扑异质性，我们展示了拓扑异构化网络（TIN）的概念，它可以被编程为许多拓扑状态。使用控制异构化反应的光潜催化剂，实现了拓扑的时空操纵。总体结果是网络聚合物可以被编程成多种具有独特且空间可定义的（热）机械性能的聚合物。在众多实际应用机会中，TIN 的独特属性可以被探索用作变形结构、自适应机器人臂和抗断裂可拉伸装置，显示出高度的设计多功能性。 TIN 概念丰富了聚合物的设计，具有扩展到具有动态共价化学变化、可异构化拓扑和可编程宏观特性的其他材料的潜力。