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Unraveling the iterative type I polyketide synthases hidden in Streptomyces [Biochemistry]
Proceedings of the National Academy of Sciences of the United States of America ( IF 11.1 ) Pub Date : 2020-03-26
Bin Wang, Fang Guo, Chunshuai Huang, Huimin Zhao

Type I polyketide synthases (T1PKSs) are one of the most extensively studied PKSs, which can act either iteratively or via an assembly-line mechanism. Domains in the T1PKSs can readily be predicted by computational tools based on their highly conserved sequences. However, to distinguish between iterative and noniterative at the module...

中文翻译:

揭示链霉菌中隐藏的I型迭代聚酮化合物合酶[生物化学]

I型聚酮化合物合酶(T1PKSs)是研究最广泛的PKS之一,可以迭代或通过装配线机制起作用。T1PKS中的结构域可以根据其高度保守的序列通过计算工具轻松预测。但是,要在模块上区分迭代和非迭代...
更新日期:2020-03-27
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