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Trends in the incidence and DALYs of bipolar disorder at global, regional, and national levels: Results from the global burden of Disease Study 2017.
Journal of Psychiatric Research ( IF 3.7 ) Pub Date : 2020-03-27 , DOI: 10.1016/j.jpsychires.2020.03.015
Hairong He 1 , Chuanyu Hu 2 , Zhenhu Ren 3 , Ling Bai 4 , Fan Gao 4 , Jun Lyu 5
Affiliation  

The objective of this study is to assess the global, regional, and national burden of bipolar disorder (BPD) from 1990 to 2017, by gender, age, and social-demographic index (SDI) from the 2017 Global Burden of Disease (GBD) study. We collected detailed information from GBD on the numbers of incidence cases and disability-adjusted life years (DALYs), age-standardized incidence rate (ASIR), and age-standardized DALYs rate (ASDR) during 1990-2017. Estimated annual percentage changes (EAPCs) were calculated to assess ASIR and ASDR trends. GBD data estimated that BPD incidences increased by 47.74%, from 3.06 million in 1990 to 4.53 million in 2017, and the DALYs increased by 54.4%, from 6.02 million in 1990 to 9.29 million in 2017. Over the 28-year period between 1990 and 2017, the ASIR and ASDR increased only slightly (EAPC = 0.14 and 0.05 for ASIR and ASDR, respectively). Subjects aged 10-19 years contributed the most to the total number of incidence cases, while those aged 20-44 years contributed the most to the number of DALYs. The ASIR and ASDR were highest in tropical Latin America and lowest in East Asia. Areas in the lowest sociodemographic index (SDI) quintile showed the highest ASIR (about 64/100,000), and those in the highest SDI quintile showed the highest ASDR (about 140/100,000). In conclusion, while the ASIR and ASDR due to BPD have been stable, the absolute incidence and DALYs remain high, which represents an increasing burden on health-care systems.

中文翻译:

全球,区域和国家级躁郁症的发病率和DALY的趋势:《 2017年疾病研究全球负担》的结果。

这项研究的目的是根据2017年全球疾病负担(GBD)中的性别,年龄和社会人口指数(SDI)评估1990年至2017年全球躁郁症(BPD)的全球,区域和国家负担研究。我们从GBD收集了1990-2017年期间的发病病例数和残疾调整生命年(DALYs),年龄标准化发病率(ASIR)和年龄标准化DALYs比率(ASDR)的详细信息。计算估计的年度百分比变化(EAPC)以评估ASIR和ASDR趋势。GBD数据估计,BPD发病率从1990年的306万增加到2017年的453万,增长了47.74%,而残疾调整生命年从1990年的602万增加到2017年的929万,增长了54.4%。 2017年,ASIR和ASDR仅略有增加(EAPC = 0.14和0。ASIR和ASDR分别为05)。10-19岁的受试者对总发病率的贡献最大,而20-44岁的受试者对DALY的贡献最大。ASIR和ASDR在热带拉丁美洲最高,在东亚最低。社会人口统计学指数最低的五分之一地区显示出最高的ASIR(大约64 / 100,000),而SDI五分位数最高的区域显示出最高的ASDR(大约140 / 100,000)。总之,尽管由于BPD引起的ASIR和ASDR保持稳定,但绝对发病率和DALY仍然很高,这对医疗保健系统构成了越来越大的负担。ASIR和ASDR在热带拉丁美洲最高,在东亚最低。社会人口统计学指数最低的五分之一地区显示出最高的ASIR(大约64 / 100,000),而SDI五分位数最高的区域显示出最高的ASDR(大约140 / 100,000)。总之,尽管由于BPD引起的ASIR和ASDR保持稳定,但绝对发病率和DALY仍然很高,这对医疗保健系统构成了越来越大的负担。ASIR和ASDR在热带拉丁美洲最高,在东亚最低。社会人口统计学指数最低的五分之一地区显示出最高的ASIR(大约64 / 100,000),而SDI五分位数最高的区域显示出最高的ASDR(大约140 / 100,000)。总之,尽管由于BPD引起的ASIR和ASDR保持稳定,但绝对发病率和DALY仍然很高,这对医疗保健系统构成了越来越大的负担。
更新日期:2020-03-27
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