High photoluminescence nitrogen, phosphorus co-doped carbon nanodots for assessment of microbial viability.,Colloids and Surfaces B: Biointerfaces

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High photoluminescence nitrogen, phosphorus co-doped carbon nanodots for assessment of microbial viability.
Colloids and Surfaces B: Biointerfaces ( IF 5.4 ) Pub Date : 2020-03-27 , DOI: 10.1016/j.colsurfb.2020.110987
Xingwang Qie ₁ , Minghui Zan ₂ , Li Li ₃ , Ping Gui ₄ , Zhimin Chang ₃ , Mingfeng Ge ₃ , Ruo-Song Wang ₅ , Zhenzhen Guo ₃ , Wen-Fei Dong ₃

Affiliation

Assessment of microbial viability plays a key role in human health protection. Optical imaging based on fluorescent dyes is a simple and convenient way to assess microbial viability. However, it is still a challenge to obtain stable, nontoxic and low-cost dyes. Herein, we prepared a nitrogen and phosphorus co-doped carbon nanodots (N, P-CDs) via a one-step solvothermal method. The prepared CDs possess plenty of functional groups and exhibit high stability, good biocompatibility, excellent photoluminescent and low toxicity. Especially, the properties of high quantum yield (89.9%) and highly negative surface charge (-41.9 mV) make the prepared N, P-CDs ideal materials for microbial differentiation. Compared with commercial dyes, our CDs are more stable, cost less, which can rapidly distinguish dead microorganisms from living ones with higher specificity.

中文翻译：

高光致发光氮，磷共掺杂碳纳米点，用于评估微生物生存力。

微生物生存能力的评估在人类健康保护中起着关键作用。基于荧光染料的光学成像是评估微生物生存力的简单便捷的方法。然而，获得稳定，无毒和低成本的染料仍然是一个挑战。在这里，我们通过一步溶剂热法制备了氮和磷共掺杂的碳纳米点（N，P-CDs）。制备的CD具有足够的官能团，并显示出高稳定性，良好的生物相容性，优异的光致发光和低毒性。特别是，高量子产率（89.9％）和高负表面电荷（-41.9 mV）的特性使所制备的N，P-CDs成为微生物分化的理想材料。与商用染料相比，我们的CD更稳定，成本更低，

更新日期：2020-03-27

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