当前位置: X-MOL 学术Chem. Soc. Rev. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Influence of nanomedicine mechanical properties on tumor targeting delivery.
Chemical Society Reviews ( IF 40.4 ) Pub Date : 2020-04-27 , DOI: 10.1039/c9cs00575g
Zheng Li 1 , Chen Xiao 1 , Tuying Yong 1 , Zifu Li 2 , Lu Gan 2 , Xiangliang Yang 2
Affiliation  

Modulating nanomedicine mechanical properties for enhanced drug delivery to tumors has attracted increasing attention in the past few decades. In this tutorial review, we analyze the impact of nanomedicine mechanical properties on in vivo transport processes and highlight the most recent advances in drug delivery efficiency and antitumor efficacy. Typical nanoparticles that have been explored for this purpose since 2000 are summarized while the methods to tune and the techniques to characterize nanomedicine mechanical properties are introduced. In the end, challenges and perspectives on tailoring nanomedicine mechanical properties for tumor targeting delivery are discussed.

中文翻译:

纳米药物力学性能对肿瘤靶向递送的影响。

在过去的几十年中,调节纳米药物的机械性能以增强向肿瘤的药物递送已引起越来越多的关注。在本教程中,我们分析了纳米药物机械性能对体内转运过程的影响,并重点介绍了药物输送效率和抗肿瘤功效方面的最新进展。总结了自2000年以来为此目的而开发的典型纳米粒子,同时介绍了调整方法和表征纳米医学机械性能的技术。最后,讨论了针对肿瘤靶向递送定制纳米药物机械性能的挑战和前景。
更新日期:2020-03-26
down
wechat
bug