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Decline in Hepatitis C Virus (HCV) Incidence in Men Who Have Sex With Men Living With Human Immunodeficiency Virus: Progress to HCV Microelimination in the United Kingdom?
Clinical Infectious Diseases ( IF 8.2 ) Pub Date : 2020-03-25 , DOI: 10.1093/cid/ciaa021
Lucy J Garvey 1 , Graham S Cooke 1, 2 , Colette Smith 3 , Christoph Stingone 4 , Indrajit Ghosh 5 , Subathira Dakshina 5 , Lakshmi Jain 5 , Laura J Waters 5 , Tabitha Mahungu 4 , Filippo Ferro 4 , Chandni Sood 1 , Carolyn Freeman 1 , Clare Phillips 6 , Rageshri Dhairyawan 7 , Ruth Burholt 6 , Harriet Sharp 6 , Sadna Ullah 7 , Yvonne Gilleece 6 , Ashley Brown 1 , Chloe Orkin 7, 8 , Alison Rodger 3, 4 , Sanjay Bhagani 4
Affiliation  

Modeling of the London hepatitis C virus (HCV) epidemic in men who have sex with men (MSM) and are living with human immunodeficiency virus (HIV) suggested that early access to direct-acting antiviral (DAA) treatment may reduce incidence. With high rates of linkage to care, microelimination of HCV within MSM living with HIV may be realistic ahead of 2030 World Health Organization targets. We examined trends in HCV incidence in the pre- and post-DAA eras for MSM living with HIV in London and Brighton, United Kingdom.

中文翻译:

与患有人类免疫缺陷病毒的男性发生性关系的男性中丙型肝炎病毒(HCV)发病率下降:英国进行HCV微消除的进展?

对与男性发生性关系(MSM),并患有人类免疫缺陷病毒(HIV)的男性进行的伦敦丙型肝炎病毒(HCV)流行病建模表明,尽早获得直接作用抗病毒(DAA)治疗可降低发病率。由于与护理的联系率很高,因此在2030年世界卫生组织制定目标之前,消除艾滋病毒的男男性接触者中HCV的微量消除可能是现实的。我们研究了英国伦敦和英国布莱顿在MSA感染HIV的达美药物滥用前后的HCV发病率趋势。
更新日期:2020-03-25
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