CT screening for early diagnosis of SARS-CoV-2 infection - Authors' reply.,The Lancet Infectious Diseases

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CT screening for early diagnosis of SARS-CoV-2 infection - Authors' reply.
The Lancet Infectious Diseases ( IF 36.4 ) Pub Date : 2020-03-26 , DOI: 10.1016/s1473-3099(20)30247-4
Heshui Shi ₁ , Xiaoyu Han ₁ , Yukun Cao ₁ , Osamah Alwalid ₁ , Chuansheng Zheng ₁

Affiliation

We appreciate the concerns raised by Yongshun Huang and colleagues regarding our Article on radiological findings in coronavirus disease 2019 (COVID-19). During the outbreak of COVID-19 in China in January, and February, 2020, timely diagnosis was a crucial step for infection control, especially in the epidemic area of Wuhan, Hubei province. However, RT-PCR kits were not sufficiently provided to hospitals in Wuhan until Jan 16, 2020. Before then, there was less capacity of kits to meet the rapidly increasing clinical demand. Furthermore, the total positive rate of RT-PCR for throat swab samples was reported to be less than 60%. The diagnostic sensitivity of viral pneumonia by chest radiography was relatively low, whereas CT had a high sensitivity for diagnosis of COVID-19, making it a potential primary tool for COVID-19 detection in epidemic areas. Additionally, according to the guideline for diagnosis and treatment of COVID-19 by the Chinese Ministry of Health (fifth trial edition), clinically suspected cases in Hubei province were mainly those with imaging features consistent with pneumonia.

更新日期：2020-03-27

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