We read with interest the Article by Michaela J Day and colleagues highlighting that bacteraemia with antibiotic-resistant extended-spectrum β-lactamase (ESBL)-producing Escherichia coli are often derived from humans, and the importance of preventing human-to-human transmission rather than transmission from livestock or food. They highlighted that E coli is now the most common bloodstream pathogen in England, UK, and is typically urinary in origin. This finding highlights the importance of rapid and effective identification and treatment of urinary tract infections (UTIs) to prevent bacteraemia caused by ESBL-producing E coli.

中文翻译：

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产生广谱β-内酰胺酶的大肠杆菌。

我们饶有兴趣地阅读了Michaela J Day及其同事的文章，重点强调了具有抗生素抗性的广谱β-内酰胺酶（ESBL）产生大肠杆菌的菌血症通常来源于人类，而预防人与人之间传播的重要性反而更为重要。而不是牲畜或食物的传播。他们强调，大肠杆菌是英国，英国现在最常见的血液病原体，起源于尿液。这一发现强调了快速有效地鉴定和治疗尿路感染（UTI）的重要性，以预防由产生ESBL的大肠杆菌引起的菌血症。