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"Negative T2 shine through" in patients with hyperglycemia and seizures: a frequently overlooked MRI pattern.
Neuroradiology ( IF 2.4 ) Pub Date : 2020-03-26 , DOI: 10.1007/s00234-020-02408-w
Horst Urbach 1 , Benjamin Berger 2 , Laszlo Solymosi 3 , Julian Zimmermann 4
Affiliation  

Epileptic seizures associated with hyperglycemia have a rare but characteristic MR imaging pattern which however is frequently missed. It consists of a T2 hypointensity and an apparent diffusion coefficient (ADC) decrease of the white matter underlying the epileptic cortex; the cortex itself may be DWI hyperintense and show a blood-brain barrier disruption. Prompt diagnosis is relevant since treatment of the hyperglycemic state rather than treatment with anti-epileptic drugs frequently interrupts the seizures. Subcortical T2 hypointensity and ADC decrease may be completely reversible.



中文翻译:

高血糖和癫痫发作的患者“ T2阴性穿透”:经常被忽略的MRI模式。

与高血糖症相关的癫痫性发作具有罕见但特征性的MR成像模式,但常常被遗漏。它由T2低强度和癫痫皮质下白质的表观扩散系数(ADC)降低组成。皮质本身可能是DWI的高信号,并显示血脑屏障破坏。及时诊断很重要,因为高血糖状态的治疗而不是抗癫痫药的治疗经常会中断癫痫发作。皮层下T2低强度和ADC降低可能是完全可逆的。

更新日期:2020-03-26
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