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CO2 enrichment: Enhancing antioxidant, antibacterial and anticancer activities in Arthrospira platensis
Food Bioscience ( IF 4.8 ) Pub Date : 2020-03-26 , DOI: 10.1016/j.fbio.2020.100575
Sameh sassi Aydi , Samir Aydi , Rihab Ben Abdallah Kolsi , Nouha Haddeji , Rami Rahmani , Naourez Ktari , Jalloul Bouajila

The effect of CO2 enrichment on the content of minerals, crude proteins, carbohydrate, and total polyphenols and flavonoids as well as antioxidant, cytotoxic and antibacterial activity of Arthrospira platensis were studied. A. platensis grown with CO2 enriched medium had less crude protein but more carbohydrate and phytochemical compounds. Increased calcium and iron contents were also obtained. CO2 seemed to increase polyphenols, flavonoids and tannins, which in turn increased antioxidant activities using the DPPH assay (IC50 = 1.64 μg mL-1). Moreover, CO2 enrichment increased antibacterial activity, namely against E. coli and S. enterica. Cytotoxicity was increased with CO2, especially with the OVCAR (IC50 = 17.5 μg mL-1) and MCF-7 (IC50 = 14.5 μg mL-1) cell lines. GC-MS analysis showed that in CO2 free medium 12 bioactive compounds were found. The most abundant compounds were hexadecanoic acid, methyl ester and n-hexadecanoic acid. However in CO2 enriched medium results showed the presence of only 7 compounds. Therefore, the use of CO2 in the production of algae may have a positive environmental benefit to reduce the carbon pollution from the atmosphere and provide a better Spirulina production and quality.



中文翻译:

富集CO 2:增强Arthrospira platensis的抗氧化,抗菌和抗癌活性

研究了CO 2富集对板兰节肢动物矿物质,粗蛋白,碳水化合物,总多酚和类黄酮含量以及抗氧化剂,细胞毒性和抗菌活性的影响用富含CO 2的培养基生长的白僵菌具有较少的粗蛋白,但具有较多的碳水化合物和植物化学化合物。还获得了增加的钙和铁含量。CO 2似乎会增加多酚,类黄酮和丹宁酸的含量,进而通过DPPH分析(IC 50  = 1.64μgmL -1)提高抗氧化活性。此外,富集CO 2增加了抗菌活性,即对大肠杆菌肠炎链球菌。CO 2会增加细胞毒性,尤其是OVCAR(IC 50  = 17.5μgmL -1)和MCF-7(IC 50  = 14.5μgmL -1)细胞系。GC-MS分析表明,在无CO 2的培养基中发现了12种生物活性化合物。最丰富的化合物是十六烷酸,甲酯和正十六烷酸。但是,在富含CO 2的培养基中,结果表明仅存在7种化合物。因此,在藻类生产中使用CO 2可能具有积极的环境效益,以减少来自大气的碳污染并提供更好的螺旋藻 生产和质量。

更新日期:2020-03-26
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