In total hip replacements (THRs), metal-on-metal (MoM) design used to be predominant in the market until 2009 when it has been shown that its wear products could cause several adverse local tissue reactions (ALTR). The leading cause of excessive MoM wear products is the tribocorrosive reaction, which is the synergism of tribology and corrosion. To mitigate this effect, inspired by the presence of tribolayer on retrieved hip implants, carbide-derived carbon (CDC) has been proposed to be a potential solution for the current problem. In this study, we successfully carburized Ti6Al4V alloy and fabricated CDC, which was characterized by X-ray diffraction (XRD), Raman spectroscopy, and scanning electron microscopy (SEM). According to the results of tribocorrosion experiments, CDC specimens presented less potential drop, less wear volume loss and lower friction coefficient in 3.6 k- and 100 k-cycle experiments. The mechanism of CDC's protection was proposed to explain the current data. Meanwhile, CDC's biocompatibility was also examined by cell proliferation and direct observation of stained actins and nuclei in cells by confocal microscopy. Combined with all collected data, it has been concluded that CDC can provide excellent protection to titanium alloy substrate with similar biocompatibility to Ti6Al4V.

在全部髋关节置换术（THR）中，金属对金属（MoM）的设计在市场上一直占主导地位，直到2009年，事实证明其磨损产品会引起多种不良的局部组织反应（ALTR）。MoM磨损产物过多的主要原因是摩擦腐蚀反应，这是摩擦学和腐蚀的协同作用。为了减轻这种影响，受取回的髋关节植入物上摩擦层的存在的启发，碳化物衍生的碳（CDC）被提议作为当前问题的潜在解决方案。在这项研究中，我们成功地渗碳了Ti6Al4V合金并制造了CDC，通过X射线衍射（XRD），拉曼光谱和扫描电子显微镜（SEM）对CDC进行了表征。根据摩擦腐蚀实验的结果，CDC标本的电位降较小，在3.6 k和100 k循环实验中，磨损量损失更少，摩擦系数更低。提出了CDC的保护机制来解释当前数据。同时，还通过细胞增殖和通过共聚焦显微镜直接观察细胞中染色的肌动蛋白和细胞核检查了CDC的生物相容性。结合所有收集到的数据，可以得出结论，CDC可以提供对Ti合金具有与Ti6Al4V相似的生物相容性的出色保护作用。