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Covid-19: risk factors for severe disease and death
The BMJ ( IF 93.6 ) Pub Date : 2020-03-26 , DOI: 10.1136/bmj.m1198 Rachel E Jordan 1 , Peymane Adab 2 , K K Cheng 2
The BMJ ( IF 93.6 ) Pub Date : 2020-03-26 , DOI: 10.1136/bmj.m1198 Rachel E Jordan 1 , Peymane Adab 2 , K K Cheng 2
Affiliation
A long list is emerging from largely unadjusted analyses, with age near the top As the covid-19 pandemic accelerates, governments are warning people at high risk to be particularly stringent in observing social distancing measures because if they become ill they are more likely to need critical care including ventilation, and to die.1 Most data on covid-19 are from China, and although most confirmed cases have been classified as mild or moderate, 14% are severe and 5% critical.2 Case fatality rates are difficult to assess with certainty but could be as high as 1%,34 which is much greater than seasonal influenza at about 0.1%. Up to 25% of people in the United Kingdom are designated high risk—including all adults aged over 70 and those with underlying health conditions such as respiratory and cardiovascular disease, and cancer.5 Strict restrictions are now in place for everyone, reducing movement outside the home to an absolute minimum, except for essential workers.6 These measures will be in place for weeks, possibly …
更新日期：2020-03-27
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