Pupillary evaluation is a crucial element of physical exams. Noting size, reactivity, and consensual response is critical in assessing for optic nerve dysfunction. We aim to establish normative data for scotopic pupillary size and function in the pediatric population in a clinical setting. Pupillometry was obtained prospectively for consecutive, normal patients < 18 years old being evaluated by Lurie Children’s Ophthalmology. Quantitative data included maximum (MAX) and minimum (MIN) diameters, constriction percentage (CON), latency (LAT), average (ACV) and maximum (MCV) constriction velocities, average dilation velocity (ADV), and 75% recovery time (T75). Iris color was noted as light, intermediate, or dark. 196 eyes of 101 participants (42.6% male, ages 1–17 years, average age 10.3 years) were analyzed. Mean MAX was 6.6 mm (5.1–8.1 mm 95% CI); MIN was 4.7 mm (3.1–6.1 mm 95% CI); CON was 30% (17–42 95% CI); LAT was 230 milliseconds (160–300 ms 95% CI); ACV was 3.70 mm/sec (2.21–5.18 mm/sec 95% CI); and ADV was 0.88 mm/sec (0.38–1.38 mm/sec 95% CI). Age had a positive correlation with MAX, MIN, and CON. 84.2 and 95.8% of participants showed resting pupil asymmetry of ≤0.5 mm and ≤ 1.0 mm, respectively. Quantitative pupillometry can be a useful tool for screening pediatric patients. We sought to establish normative data in this group. We found males to have significantly greater MCV and CON than females (p < 0.05). Also, age had a positive correlation with MAX, MIN, and CON.

中文翻译：

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建立儿童数量瞳孔计量标准数据库

瞳孔评估是身体检查的关键要素。注意大小，反应性和自愿反应对于评估视神经功能障碍至关重要。我们的目标是在临床环境中建立小儿人群暗视瞳孔大小和功能的规范数据。通过Lurie儿童眼科评估对连续的18岁以下正常患者进行前视镜测量。定量数据包括最大（MAX）和最小（MIN）直径，收缩百分比（CON），潜伏期（LAT），平均（ACV）和最大（MCV）收缩速度，平均扩张速度（ADV）和75％的恢复时间（ T75）。虹膜颜色为浅色，中间色或深色。分析了101名参与者的196眼（男性42.6％，年龄1-17岁，平均年龄10.3岁）。平均MAX为6.6毫米（5.1-8.1毫米95％CI）；MIN为4.7毫米（3.1-6.1毫米95％CI）；CON为30％（17-42 95％CI）；LAT为230毫秒（160-300毫秒95％CI）；ACV为3.70毫米/秒（2.21-5.18毫米/秒95％CI）；而ADV为0.88毫米/秒（95％CI为0.38–1.38毫米/秒）。年龄与MAX，MIN和CON呈正相关。分别有84.2和95.8％的参与者表现出静息瞳孔不对称度分别≤0.5 mm和≤1.0 mm。定量瞳孔测量法可能是筛查儿科患者的有用工具。我们试图在该组中建立规范性数据。我们发现男性的MCV和CON明显高于女性（p <0.05）。另外，年龄与MAX，MIN和CON呈正相关。年龄与MAX，MIN和CON呈正相关。分别有84.2和95.8％的参与者表现出静息瞳孔不对称度分别≤0.5 mm和≤1.0 mm。定量瞳孔测量法可能是筛查儿科患者的有用工具。我们试图在该组中建立规范性数据。我们发现男性的MCV和CON明显高于女性（p <0.05）。另外，年龄与MAX，MIN和CON呈正相关。年龄与MAX，MIN和CON呈正相关。分别有84.2和95.8％的参与者表现出静息瞳孔不对称度分别≤0.5 mm和≤1.0 mm。定量瞳孔测量法可能是筛查儿科患者的有用工具。我们试图在该组中建立规范性数据。我们发现男性的MCV和CON明显高于女性（p <0.05）。另外，年龄与MAX，MIN和CON呈正相关。