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CAR Engineering Comes to Macrophages.
Cancer Discovery ( IF 29.7 ) Pub Date : 2020-05-01 , DOI: 10.1158/2159-8290.cd-nb2020-019
American Association for Cancer Research

Human macrophages equipped with chimeric antigen receptor constructs infiltrate solid tumors, ingest malignant tissue, and stimulate adaptive immunity in mouse models. Several new biotech companies are racing to bring the technology into clinical trials.

中文翻译:

汽车工程来了巨噬细胞。

配备有嵌合抗原受体构建体的人类巨噬细胞浸润实体瘤,摄入恶性组织,并在小鼠模型中刺激适应性免疫。几家新的生物技术公司正在竞相将该技术用于临床试验。
更新日期:2020-05-01
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