Cardiac arrhythmias in Dravet syndrome: an observational multicenter study.,Annals of Clinical and Translational Neurology

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Cardiac arrhythmias in Dravet syndrome: an observational multicenter study.
Annals of Clinical and Translational Neurology ( IF 4.4 ) Pub Date : 2020-03-24 , DOI: 10.1002/acn3.51017
Sharon Shmuely _{1,

2} , Rainer Surges _{3,

4} , Robert M Helling ₁ , W Boudewijn Gunning ₁ , Eva H Brilstra ₅ , Judith S Verhoeven ₆ , J Helen Cross ₇ , Sanjay M Sisodiya _{2,

8} , Hanno L Tan _{9,

10} , Josemir W Sander _{1,

2,

8} , Roland D Thijs _{1,

2,

11}

Affiliation

Stichting Epilepsie Instellingen Nederland - SEIN, Achterweg 5, 2103 SW Heemstede, Dokter Denekampweg 20, 8025 BV, Zwolle, The Netherlands.
NIHR University College London Hospitals Biomedical Research Centre, UCL Queen Square Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
Department of Epileptology, University Hospital Bonn, Bonn, Germany.
Centre for Rare Diseases Bonn (ZSEB), University Hospital Bonn, Bonn, Germany.
Department of Medical Genetics, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
Academic Centre for Epileptology Kempenhaeghe, 5590AB Heeze, Heeze, The Netherlands.
UCL NIHR BRC Great Ormond Street Institute of Child Health (ICH), 30 Guilford St, London, WC1N 1EH, UK.
Chalfont Centre for Epilepsy, Bucks, SL9 0RJ, UK.
Heart Centre, Department of Experimental and Clinical Cardiology, Amsterdam University Medical Centres, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Netherlands Heart Institute, Moreelsepark 1, 3511 EP, Utrecht, The Netherlands.
Department of Neurology, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

We ascertained the prevalence of ictal arrhythmias to explain the high rate of sudden unexpected death in epilepsy (SUDEP) in Dravet syndrome (DS).

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