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Critical analysis of the value of the rabbit median nerve model for biomedical research on peripheral nerve grafts.
Journal of Tissue Engineering and Regenerative Medicine ( IF 3.1 ) Pub Date : 2020-03-23 , DOI: 10.1002/term.3036
Giulia Ronchi 1, 2 , Giovanna Gambarotta 1 , Michela Morano 1, 2 , Federica Fregnan 1, 2 , Pierfrancesco Pugliese 3 , Pierluigi Tos 4 , Stefano Geuna 1, 2 , Kirsten Haastert-Talini 5
Affiliation  

The rabbit has been proposed to represent an animal model that allows studying peripheral nerve regeneration across extended gap lengths. We describe here our experiences with the rabbit median nerve model and the obstacles it comes along with. This short communication is meant to inform the community and to prevent other researcher from investing time and animal lives in a model with low translational power.

中文翻译:

兔正中神经模型对周围神经移植物生物医学研究的价值的临界分析。

已经提出了代表一种代表动物模型的兔子,该模型允许研究扩展的间隙长度上的周围神经再生。我们在这里描述了我们对兔子正中神经模型的经验及其带来的障碍。这种简短的交流旨在告知社区,并防止其他研究人员在翻译能力低的模型中投入时间和动物生命。
更新日期:2020-03-23
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