Titanium as an Instant Adhesive for Biological Soft Tissue,Advanced Materials Interfaces

当前位置： X-MOL 学术 › Adv. Mater. Interfaces › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Titanium as an Instant Adhesive for Biological Soft Tissue
Advanced Materials Interfaces ( IF 4.3 ) Pub Date : 2020-03-23 , DOI: 10.1002/admi.201902089
Masahiro Okada ₁ , Emilio Satoshi Hara ₁ , Atsushi Yabe _{1,

2} , Kei Okada ₃ , Yo Shibata ₄ , Yasuhiro Torii ₂ , Takayoshi Nakano ₅ , Takuya Matsumoto ₁

Affiliation

A variety of polymer‐ and ceramic‐based soft‐tissue adhesives have been developed as alternatives to surgical sutures, yet several disadvantages regarding the mechanical properties, biocompatibility, and handling hinder their further application particularly when applied for immobilization of implantable devices. Here, it is reported that a biocompatible and tough metal, titanium (Ti), shows instant and remarkable adhesion properties after acid treatment, demonstrated by ex vivo shear adhesion tests with mouse dermal tissues. Importantly, in vivo experiments demonstrate that the acid‐treated Ti can easily and stably immobilize a device implanted in the mouse subcutaneous tissue. Collectively, the acid‐treated Ti is shown as a solid‐state instant adhesive material for biological soft tissues, which can have diverse applications including immobilization of body‐implantable devices.

中文翻译：

钛作为生物软组织的即时粘合剂

已经开发出多种基于聚合物和陶瓷的软组织粘合剂作为手术缝合的替代方法，但是有关机械性能，生物相容性和操作性的一些缺点阻碍了它们的进一步应用，尤其是在固定植入式设备时。在这里，据报道，一种生物相容性强韧的金属钛（Ti）在酸处理后显示出即时而显着的粘合性能，这是通过对小鼠皮肤组织的离体剪切粘合力测试证明的。重要的是，体内实验表明，经过酸处理的Ti可以轻松，稳定地固定植入小鼠皮下组织的装置。总的来说，酸处理过的Ti被证明是一种用于生物软组织的固态即时粘合材料，

更新日期：2020-03-23

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南11