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Exploration of an arabinogalactan isolated from Odina wodier Roxb.: Physicochemical, compositional characterisations and functional attributes
Polymers for Advanced Technologies ( IF 3.1 ) Pub Date : 2020-03-25 , DOI: 10.1002/pat.4908
Arnab De 1 , Bhaskar Das 1 , Debmalya Mitra 1 , Asish K Sen 2 , Amalesh Samanta 1
Affiliation  

Exudate gum polysaccharides have a diverse range of functionalities in food, cosmetics, textiles, biomedical, pharmaceutical and other industries for centuries. The potentiality of gum odina as tablet binder, coacervates (chitosan‐gum odina complex) for colon‐targeted drug delivery system and also as prebiotic with immunomodulating properties was reported earlier. Since no detail study of the physicochemical, functional properties of the gum has been reported, the present investigation deals with physicochemical, compositional and functional characterisations of purified gum odina (PGO) for adopting in food and pharmaceutical industry. PGO, an arabinogalactan, was obtained by ethanol precipitation from exudates (gum odina) of tropical deciduous plant Odina wodier Roxb. Colour profiling of PGO including L* (87.74 ± 0.42), a* (1.73 ± 0.65) and b* (7.79 ± 0.58) was determined. Physicochemical parameters revealed good flow ability and compressibility desired for an excipient. Concentration‐dependent surface tension was measured by du Noüy ring method. Rheological study showed pseudoplastic behaviour of PGO dispersion. Sugar analysis by gas liquid chromatography indicated presence of arabinogalactan in PGO. Size exclusion chromatography of PGO revealed two high‐molecular‐weight components PGO‐I (95%, Arabinose:Galactose :: 1:1.6) and PGO‐II (5%, Arabinose:Galactose :: 1:4). Further characterisations of PGO by means of CHNS, FTIR, differential scanning calorimetry, X‐ray diffraction, transmission electron microscopy, scanning electron microscopy and energy‐dispersive X‐ray diffraction, conductivity, pH, zeta potential analysis and antioxidant activity indicated typical polysaccharide characteristics. Collectively, this work established the fundamental properties of PGO and the results presented here will facilitate the applications of PGO as sustainable food additive, pharmaceutical excipient for commercial adoption.

中文翻译:

从Odina wodier Roxb分离的阿拉伯半乳聚糖的探索:物理化学,组成特征和功能属性

几个世纪以来,渗出的树胶多糖在食品,化妆品,纺织品,生物医学,制药和其他行业中具有多种功能。早先报道了口香糖odina作为片剂粘合剂,凝聚层(壳聚糖-胶odina复合物)对于结肠靶向药物递送系统以及作为具有免疫调节特性的益生元的潜力。由于尚未报告对口香糖的物理化学,功能特性进行详细研究,因此,本研究涉及在食品和制药行业中采用的纯胶基奥迪纳(PGO)的物理化学,组成和功能特性。PGO,一种阿拉伯半乳聚糖,是通过乙醇沉淀从热带落叶植物Odina wodier Roxb的分泌液(口香糖odina)中获得的。PGO的颜色配置文件包括L *(87.74±0.42),a *(1.73±0.65)和b*(7.79±0.58)已确定。物理化学参数显示了赋形剂所需的良好流动性和可压缩性。浓度依赖性表面张力通过duNoüy环法测量。流变学研究表明PGO分散液具有假塑性行为。通过气相色谱法的糖分析表明在PGO中存在阿拉伯半乳聚糖。PGO的尺寸排阻色谱法显示了两个高分子量组分PGO-I(95%,阿拉伯糖:半乳糖:: 1:1.6)和PGO-II(5%,阿拉伯糖:半乳糖:: 1:4)。通过CHNS,FTIR,差示扫描量热法,X射线衍射,透射电子显微镜,扫描电子显微镜和能量分散X射线衍射,电导率,pH,ζ电位分析和抗氧化活性表明典型的多糖特性。总的来说,这项工作确立了PGO的基本特性,此处介绍的结果将促进PGO作为可持续食品添加剂,商业化药用赋形剂的应用。
更新日期:2020-03-25
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