Oxidative Ring‐Opening of 1H‐Pyrazol‐5‐amines and Its Application in Constructing Pyrazolo–Pyrrolo–Pyrazine Scaffolds by Domino Cyclization,European Journal of Organic Chemistry

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Oxidative Ring‐Opening of 1H‐Pyrazol‐5‐amines and Its Application in Constructing Pyrazolo–Pyrrolo–Pyrazine Scaffolds by Domino Cyclization
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2020-03-25 , DOI: 10.1002/ejoc.202000265
Lei Pan ₁ , Feng Jin ₁ , Rui Fu ₁ , Ke Gao ₁ , Shaofang Zhou ₁ , Xiaoguang Bao ₁

Affiliation

A concise approach to synthesize 3H‐pyrazolo[3,4‐e]pyrrolo[1,2‐a]pyrazine derivatives via oxidative ring‐opening of 1H‐pyrazol‐5‐amines under mild and transition‐metal‐free conditions is described herein.