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Treatment of PD-1/PD-L1 Inhibitor-Induced Dermatitis Resolves Concomitant Eruptive Keratoacanthomas.
JAMA Dermatology ( IF 10.9 ) Pub Date : 2020-05-01 , DOI: 10.1001/jamadermatol.2020.0176
Lauren D Crow 1 , Ifeoma Perkins 2 , Amanda R Twigg 1 , Marlys S Fassett 1 , Philip E LeBoit 3 , Timothy G Berger 1 , Rita Khodosh 1
Affiliation  

Patients who develop eruptive keratoacanthomas (KAs) in the setting of PD-1/PD-L1 inhibitor–induced dermatitis are challenging to treat and discontinue immunotherapy at a much higher rate than those without KAs.1-4 We successfully used 3 different nonsurgical anti-inflammatory therapies to treat both immunotherapy-induced dermatitis and concomitant eruptive KAs.



中文翻译:

PD-1 / PD-L1抑制剂引起的皮炎的治疗可解决伴随的爆发性角棘皮瘤。

在PD-1 / PD-L1抑制剂引起的皮炎的情况下发展为爆发性角膜棘皮瘤(KAs)的患者,与没有KAs的患者相比,治疗和中断免疫疗法的挑战性更高。1 -4我们成功地使用了3种不同的非手术抗炎治疗方法,以治疗免疫治疗引起的皮炎和随之而来的爆发性KA。

更新日期:2020-05-01
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