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DBC1, p300, HDAC3, and Siah1 coordinately regulate ELL stability and function for expression of its target genes [Biochemistry]
Proceedings of the National Academy of Sciences of the United States of America ( IF 11.1 ) Pub Date : 2020-03-24
Subham Basu, Mahesh Barad, Dipika Yadav, Arijit Nandy, Bidisha Mukherjee, Jit Sarkar, Partha Chakrabarti, Satinath Mukhopadhyay, Debabrata Biswas

Among all of the Super Elongation Complex (SEC) components, ELL1 (also known as ELL) is the only bona fide elongation factor that directly stimulates transcription elongation by RNA polymerase II. However, the mechanism(s) of functional regulation of ELL1 (referred to as ELL hereafter), through its stabilization, is completely unknown. Here,...

中文翻译:

DBC1,p300,HDAC3和Siah1协同调节ELL的稳定性和表达其靶基因的功能[生物化学]

在所有的超级延伸复合体(SEC)组件中,ELL1(也称为ELL)是唯一直接刺激RNA聚合酶II转录延伸的真正延伸因子。然而,完全不知道ELL1(以下称为ELL)的功能调节的机制。这里,...
更新日期:2020-03-26
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